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Irvine Medical Office Property Goes for Over $16 Mil

10/15/25

Creek Medical Buildings, a three-building, 43.4k sf medical office property in Irvine, traded hands in a recent $16.25 mil ($375/sf) deal. The property is located at 37, 39 and 41 Creek Rd, west of Jeffrey Rd and south of Barranca Pkwy.

Photo: Sanduku Inc.
Photo: Sanduku Inc.
Built in 1986, the property is fully occupied. The three buildings are strategically positioned within Irvine's highly sought-after healthcare corridor in the Woodbridge neighborhood of Irvine. The property benefits from exceptional connectivity, offering seamless access to major transportation arteries, a robust and affluent demographic, and a concentration of leading medical providers.

CBRE National Office Partners’ Anthony DeLorenzo, along with Sammy Cemo, Bryan Johnson and Harry Su, represented the seller in the transaction.

“Creek Medical Buildings offered a compelling opportunity to acquire a fully leased medical office asset in one of Orange County’s most desirable healthcare hubs,” said DeLorenzo. “The property’s strong tenant mix, below-market rents, and prime location in Irvine position it well for long-term value creation.”




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