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10/15/25
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Creek Medical Buildings, a three-building, 43.4k sf medical office property in Irvine, traded hands in a recent $16.25 mil ($375/sf) deal. The property is located at 37, 39 and 41 Creek Rd, west of Jeffrey Rd and south of Barranca Pkwy.
Built in 1986, the property is fully occupied. The three buildings are strategically positioned within Irvine's highly sought-after healthcare corridor in the Woodbridge neighborhood of Irvine. The property benefits from exceptional connectivity, offering seamless access to major transportation arteries, a robust and affluent demographic, and a concentration of leading medical providers.
CBRE National Office Partners’ Anthony DeLorenzo, along with Sammy Cemo, Bryan Johnson and Harry Su, represented the seller in the transaction.
“Creek Medical Buildings offered a compelling opportunity to acquire a fully leased medical office asset in one of Orange County’s most desirable healthcare hubs,” said DeLorenzo. “The property’s strong tenant mix, below-market rents, and prime location in Irvine position it well for long-term value creation.”
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